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基于计算机的连续无创血压和心率变异性分析——清醒和睡眠期间的方法及正常值

Computer-based analysis of continuous non-invasive blood pressure and heart rate variability-methodology and normal values during wakefulness and sleep.

作者信息

Litscher G, Schwarz G, Pfurtscheller G

机构信息

AG für Biomedizinische Technik, Karl-Franzens-Universität Graz.

出版信息

Biomed Tech (Berl). 1993 Apr;38(4):62-7. doi: 10.1515/bmte.1993.38.4.62.

DOI:10.1515/bmte.1993.38.4.62
PMID:8507804
Abstract

Polysomnographic recordings were made in 10 healthy male adult subjects (mean age 25.1 +/- 2.8 years). Parameters were obtained from continuous non-invasive measurement of blood pressure and from heart rate spectra analysed both in the waking state and during sleep (stage 4). The total heart rate variability (mean +/- SE) was not significantly diminished (p < 0.2; paired t-test) during stage 4 sleep (6.2 +/- 0.5%) as compared with the waking state (7.1 +/- 0.5%). The relative heart rate variability coefficient within the frequency band HRV-II ((3-9)/min) was, however, significantly higher (p < 0.001) during slow-wave sleep (0.55 +/- 0.04) than during wakefulness (0.34 +/- 0.04). This fact is in accordance with results concerning an estimated value of the baroreflex sensitivity, which was also significantly higher (p < 0.001) during sleep stage 4 (7.0 +/- 0.8 ms/mmHg vs. 10.4 +/- 1.4 mmHg).

摘要

对10名健康成年男性受试者(平均年龄25.1±2.8岁)进行了多导睡眠图记录。参数取自清醒状态和睡眠(第4阶段)期间连续无创血压测量以及心率谱分析。与清醒状态(7.1±0.5%)相比,第4阶段睡眠期间总心率变异性(平均±标准误)没有显著降低(p<0.2;配对t检验)(6.2±0.5%)。然而,在慢波睡眠期间,HRV-II频段((3 - 9)/分钟)内的相对心率变异系数显著高于清醒期间(p<0.001)(0.55±0.04比0.34±0.04)。这一事实与关于压力反射敏感性估计值的结果一致,压力反射敏感性在第4阶段睡眠期间也显著更高(p<0.001)(7.0±0.8毫秒/毫米汞柱对10.4±1.4毫米汞柱)。

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