80S核糖体对RA-XII的构象识别：1H NMR光谱中的微分线宽研究
Conformational recognition of RA-XII by 80S ribosomes: a differential line broadening study in 1H NMR spectroscopy.
作者信息
Morita H, Yamamiya T, Takeya K, Itokawa H, Sakuma C, Yamada J, Suga T
机构信息
Tokyo College of Pharmacy, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1993 Apr;41(4):781-3. doi: 10.1248/cpb.41.781.
PMID:8508481
Abstract
1H NMR spectroscopy has been used to demonstrate specific binding of rat 80S ribosomes to the major conformer of an antitumor bicyclic hexapeptidic glucoside, RA-XII, isolated from Rubia cordifolia, in a fast exchange process.
摘要
1H核磁共振光谱已被用于证明大鼠80S核糖体在快速交换过程中与从茜草中分离出的一种抗肿瘤双环六肽葡萄糖苷RA-XII的主要构象体的特异性结合。
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