Fankhauser F, Kwasniewska S
Universität Bern, Lindenhofspital.
Klin Monbl Augenheilkd. 1993 Mar;202(3):180-7.
Various sclerostomy procedures, performed ab interno and ab externo have found increasing interest for some time. With few exceptions, invasive procedures are described, in which laser energy is transmitted by means of specially designed fibers and probes ab interno and ab externo to the perforation site. Laser energy sources, ranging from the UV through the visible to the IR range have been described. Thus far, no detailed models quantifying the ablation mechanism of such sclerostomy procedures have been published. All such procedures have in common that the wavelength of the laser should be matched to water absorption bands. Now more sophisticated models describing the action mechanism of various lasers begin to emerge. A system described by us takes advantage of the high efficiency of rapid steam explosions occurring in a closed space, i.e. in the region delimited by the probe end and the fistula bottom. The high efficiency of such mechanisms has been verified in model experiments on porcine eyes in vitro. Electron microscopical results also show that the amount of thermal damage is negligible and that there is very little wavelength-dependence. This permits the adoption of "common" laser energy sources such as diode and Nd:YAG lasers. The clinical survival probability of fistulas as related to the amount of collateral damage is controversial.
一段时间以来,各种内路和外路巩膜造口术越来越受到关注。除了少数例外,所描述的都是侵入性手术,其中激光能量通过专门设计的光纤和探头从内路和外路传输到穿孔部位。已经描述了从紫外线到可见光再到红外范围的激光能量源。到目前为止,尚未发表量化此类巩膜造口术消融机制的详细模型。所有这些手术的共同之处在于激光波长应与水吸收带相匹配。现在,描述各种激光作用机制的更复杂模型开始出现。我们描述的一种系统利用了在封闭空间(即由探头末端和瘘管底部界定的区域)中发生的快速蒸汽爆炸的高效率。这种机制的高效率已在猪眼的体外模型实验中得到验证。电子显微镜结果还表明,热损伤量可以忽略不计,并且波长依赖性很小。这允许采用“普通”激光能量源,如二极管激光器和钕:钇铝石榴石激光器。瘘管的临床存活概率与附带损伤量的关系存在争议。