Schmitz-Rode T, Timmermans H, Uchida B, Kichikawa K, Nishida N, Günther R W, Rösch J
Department of Diagnostic Radiology, University of Technology Aachen, Germany.
Radiology. 1993 Jul;188(1):95-100. doi: 10.1148/radiology.188.1.8511323.
A mechanical vascular occluder was studied in eight pigs to test its efficacy in arteries of different diameters, stability over time, and safety in placement. The main component is a self-expandable spindle made of tubular stainless steel mesh. Simple steel spindles, double spindles, and Dacron-core spindles were placed in the common carotid artery, main renal artery, renal artery branches, and infrarenal aorta. Follow-up arteriograms were obtained immediately, 30-60 minutes, and (except for aortic spindles) 7 days after deployment. The left common carotid artery was occluded in all pigs, regardless of spindle type. In the main renal artery and its branches, simple steel spindles did not achieve complete occlusion. Double and Dacron-core spindles produced immediate occlusion without recanalization on the 1-week follow-up arteriogram, except for one spindle with an incomplete Dacron core and two spindles that did not completely fill the arterial lumen. Two Dacron-core spindles achieved immediate complete occlusion of the infrarenal aorta. No migration was seen with any spindle.
在八头猪身上对一种机械性血管封堵器进行了研究，以测试其在不同直径动脉中的疗效、随时间的稳定性以及放置的安全性。其主要部件是由管状不锈钢网制成的自膨胀纺锤体。将简单钢纺锤体、双纺锤体和涤纶芯纺锤体分别放置在颈总动脉、肾动脉主干、肾动脉分支和肾下腹主动脉中。在放置后立即、30 - 60分钟以及（肾下腹主动脉纺锤体除外）7天后获取随访血管造影照片。无论纺锤体类型如何，所有猪的左颈总动脉均被封堵。在肾动脉主干及其分支中，简单钢纺锤体未实现完全封堵。双纺锤体和涤纶芯纺锤体在1周随访血管造影照片上实现了即刻封堵且无再通，只有一个涤纶芯不完全的纺锤体以及两个未完全填充动脉腔的纺锤体除外。两个涤纶芯纺锤体实现了肾下腹主动脉的即刻完全封堵。未观察到任何纺锤体发生移位。
