阿尔茨海默病综合视觉功能障碍的筛查试验。
A screening test for integrative visual dysfunction in Alzheimer's disease.
作者信息
Trobe J D, Butter C M
机构信息
W. K. Kellogg Eye Center, Ann Arbor, MI 49105.
出版信息
Arch Ophthalmol. 1993 Jun;111(6):815-8. doi: 10.1001/archopht.1993.01090060103031.
OBJECTIVE
To develop a screening test to help ophthalmologists detect visually symptomatic patients with as yet undiagnosed Alzheimer's disease.
DESIGN
Administration of a battery of tests consisting of items modified from existing psychometric materials to decrease examination time and increase ease of scoring.
PARTICIPANTS
Fourteen patients with Alzheimer's disease and prominent visual symptoms; 53 control subjects matched to the patients with Alzheimer's disease for age, sex, and educational level; and 22 patients with subnormal visual acuity or visual fields who did not have Alzheimer's disease.
RESULTS
The novel battery of tests distinguished all 14 visually symptomatic patients with Alzheimer's disease from patients without Alzheimer's disease and control subjects.
CONCLUSION
This battery of tests should enhance the ophthalmologic detection of Alzheimer's disease.
目的
开发一种筛查测试，以帮助眼科医生检测出有视觉症状但尚未确诊的阿尔茨海默病患者。
设计
采用一组测试，这些测试项目改编自现有的心理测量材料，以减少检查时间并提高评分的简便性。
参与者
14名有明显视觉症状的阿尔茨海默病患者；53名在年龄、性别和教育水平上与阿尔茨海默病患者相匹配的对照受试者；以及22名视力或视野低于正常水平且无阿尔茨海默病的患者。
结果
这组新的测试能够将所有14名有视觉症状的阿尔茨海默病患者与无阿尔茨海默病的患者及对照受试者区分开来。
结论
这组测试应能加强眼科对阿尔茨海默病的检测。
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