Henness A M, Theilen G H, Lewis J P
Am J Vet Res. 1977 Apr;38(4):521-4.
Cats frequently develop a variety of spontaneous hemolymphatic noeplasias. Long-term remissions in the nonlymphatic leukemic cat are difficult to obtain; therefore, more successful chemotherapeutic agents are sought for disease control. The purpose in the present study is to describe the clinical investigation of 3 antineoplastic drugs given to 23 normal cats. The cats tolerated doxorubican given at the dose level of 30 mg/m2 of body surface area once every 3 weeks; daunomycin, 15 to 30 mg/m2 once every 3 weeks; and 6-thioguanine, 25 mg/m2 for 5 days every 20 to 30 days.
猫经常会患上各种自发性血液淋巴肿瘤。非淋巴细胞白血病猫很难实现长期缓解；因此，人们在寻找更有效的化疗药物来控制疾病。本研究的目的是描述对23只正常猫使用3种抗肿瘤药物的临床研究。猫能耐受每3周一次、剂量为30毫克/平方米体表面积的阿霉素；每3周一次、剂量为15至30毫克/平方米的柔红霉素；以及每20至30天一次、每次25毫克/平方米、持续5天的6-硫鸟嘌呤。
