Odelowo E O, Anjorin A S
Department of Surgery, University of Ilorin, Nigeria.
West Afr J Med. 1993 Jan-Mar;12(1):65-72.
The prognosis for carcinoma of the oesophagus is generally dismal especially when patients present late. Any clues to early diagnosis and management and identification of rapidly progressive variants are therefore helpful. Reports and review of the literature are presented with respect to four unusual cases of oesophageal carcinoma treated in the University of Ilorin Teaching Hospital in 1985 and 1986. Four men aged 59, 60, 55 and 60 years respectively presented with multiple polypoid carcinoma of the oesophagus, malignant oesophago-bronchial fistula at the level of the left main stem bronchus, achalasia co-existing with oesophago-gastric carcinoma and a small focus of carcinoma of the distal thoracic oesophagus presenting with widespread thoracic metastases and malignant pleural effusion mimicking advanced bronchogenic carcinoma. The unusual clinico-pathological features with the autopsy findings in the last case can influence diagnosis, management and prognosis of oesophageal cancer in general and of such cancer associated with pre-malignant conditions like achalasia and oesophageal polyps in particular.
食管癌的预后通常很差,尤其是患者就诊较晚时。因此,任何有助于早期诊断、治疗以及识别快速进展型变体的线索都很有帮助。本文报告并回顾了1985年和1986年在伊洛林大学教学医院治疗的4例不寻常食管癌病例的相关文献。4名男性患者,年龄分别为59岁、60岁、55岁和60岁,分别患有食管多发性息肉样癌、左主支气管水平的恶性食管支气管瘘、贲门失弛缓症合并食管胃癌,以及胸段远端食管小癌灶伴广泛胸段转移和恶性胸腔积液,后者酷似晚期支气管源性癌。最后一例病例的不寻常临床病理特征及尸检结果,总体上会影响食管癌的诊断、治疗和预后,尤其会影响与贲门失弛缓症和食管息肉等癌前病变相关的此类癌症的诊断、治疗和预后。