Uehara Y
Uehara Small Animal Hospital, Kumamoto, Japan.
J Vet Med Sci. 1993 Apr;55(2):307-12. doi: 10.1292/jvms.55.307.
The pulmonary artery blood flow was determined in 40 dogs by pulsed Doppler echocardiography as a non-invasive means for estimating pulmonary artery pressure. Most of these dogs had become infected with heartworm disease which has been known to often cause pulmonary artery hypertension. From the flow velocity profile, four parameters, i.e., the Doppler tracing pattern, right ventricular ejection acceleration time (AT), and the ratios of AT to heart rate (AT/HR) and right ventricular ejection time (AT/ET), were obtained and their correlations with the pulmonary artery pressure determined invasively were investigated. Although the morphological pattern of flow velocity hardly allowed quantitative estimation of the pulmonary artery pressure, a relatively good negative correlation (P < 0.01) was obtained between the systolic pulmonary artery pressure and AT (r = 0.71), AT/HR (r = -0.67) or AT/ET (r = -0.84). The present results indicate that pulsed Doppler echocardiography is applicable to the estimation of pulmonary artery pressure and that AT/ET has the closest correlation with directly measured pulmonary artery pressure.
通过脉冲多普勒超声心动图对40只犬的肺动脉血流进行了测定，以此作为估计肺动脉压力的一种非侵入性方法。这些犬中的大多数已感染心丝虫病，已知该病常导致肺动脉高压。从流速剖面中获取了四个参数，即多普勒描记图、右心室射血加速时间（AT）以及AT与心率的比值（AT/HR）和右心室射血时间的比值（AT/ET），并研究了它们与通过侵入性方法测定的肺动脉压力之间的相关性。尽管流速的形态模式几乎无法对肺动脉压力进行定量估计，但收缩期肺动脉压力与AT（r = 0.71）、AT/HR（r = -0.67）或AT/ET（r = -0.84）之间获得了相对良好的负相关（P < 0.01）。目前的结果表明，脉冲多普勒超声心动图适用于估计肺动脉压力，并且AT/ET与直接测量的肺动脉压力具有最密切的相关性。
