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发育性阅读障碍的神经学

Neurology of developmental dyslexia.

作者信息

Galaburda A M

机构信息

Department of Neurology, Beth Israel Hospital, Boston, Massachusetts.

出版信息

Curr Opin Neurobiol. 1993 Apr;3(2):237-42. doi: 10.1016/0959-4388(93)90216-l.

Abstract

Developmental dyslexia was until recently considered to belong solely in the domain of educational psychology. With the advent of better theories on language and reading, and better methods for assessing the structure and function of living human brains and for determining genetic transmission, dyslexia is now poised to become a focal concern of cognitive neuroscience, neurology, and genetic research. Still unresolved are questions relating to how much a reading disability represents a normal variation or a separate pathological entity, and whether the cognitive disorder is primarily cognitive, or secondary to a disorder in early perception. Recent findings from neuroanatomy, neurophysiology, neuropsychology, and genetics research are reviewed. (This review is an updated version of a review first published in Current Opinion In Neurology and Neurosurgery 1992, 5:71-76.)

摘要

直到最近,发育性阅读障碍还被认为仅属于教育心理学领域。随着关于语言和阅读的更完善理论的出现,以及评估活体人类大脑结构和功能及确定基因传递的更优方法的出现,阅读障碍现在有望成为认知神经科学、神经病学和基因研究的一个重点关注问题。与阅读障碍在多大程度上代表正常变异或独立的病理实体相关的问题,以及认知障碍主要是认知性的还是继发于早期感知障碍的问题,仍然没有得到解决。本文综述了神经解剖学、神经生理学、神经心理学和遗传学研究的最新发现。(本综述是首次发表于《神经病学与神经外科当前观点》1992年第5卷第71 - 76页的一篇综述的更新版本。)

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