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改良腹膜后淋巴结清扫术治疗睾丸肿瘤:解剖学入路、手术技术及结果

Modified retroperitoneal lymphadenectomy for testicular tumor: anatomical approach, operative technique and results.

作者信息

Hobisch A, Colleselli K, Ennemoser O, Horninger W, Poisel S, Janetschek G, Bartsch G

机构信息

Department of Urology, University of Innsbruck, Austria.

出版信息

Eur Urol. 1993;23 Suppl 2:39-43. doi: 10.1159/000474701.

Abstract

Between January 1988 and June 1992, 56 patients underwent nerve-preserving retroperitoneal lymphadenectomy at the Department of Urology, University of Innsbruck. In 23 patients stage I, and in 33 patients stage II testicular tumors were found (staging according to the criteria recommended in Lugano 1979). Orchiectomy and subsequent lymphadenectomy within the boundaries described by Weissbach's group were performed for stage I tumors. In patients presenting with stage IIa or IIb tumors modified retroperitoneal lymphadenectomy within the boundaries suggested by Colleselli's group was performed. In stage IIc patients the residual tumor was resected after three cycles of polychemotherapy. If possible, nerve-sparing lymphadenectomy was performed. By adapting the operative technique to the respective tumor stage antegrade ejaculation could be preserved in 47 of these 56 patients. Semen analysis was carried out in 22 patients. The results in patients with stages I and IIa tumors were excellent, while in stages IIb and IIc patients' exocrine testicular function was considerably worse due to inductive polychemotherapy. None of the patients had a retroperitoneal recurrence. Of all 56 patients only one had a relapse in the lung (1.7%). The average follow-up period was 29 months.

摘要

1988年1月至1992年6月期间,因斯布鲁克大学泌尿外科为56例患者实施了保留神经的腹膜后淋巴结清扫术。其中23例患者为Ⅰ期睾丸肿瘤,33例患者为Ⅱ期睾丸肿瘤(分期依据1979年卢加诺推荐的标准)。对于Ⅰ期肿瘤患者,实施了睾丸切除术及随后在魏斯巴赫团队描述的范围内进行的淋巴结清扫术。对于呈现Ⅱa期或Ⅱb期肿瘤的患者,在科莱塞利团队建议的范围内实施了改良腹膜后淋巴结清扫术。对于Ⅱc期患者,在三个周期的多药化疗后切除残留肿瘤。若有可能,则实施保留神经的淋巴结清扫术。通过使手术技术适应各自的肿瘤分期,这56例患者中有47例保留了顺行射精功能。对22例患者进行了精液分析。Ⅰ期和Ⅱa期肿瘤患者的结果极佳,而Ⅱb期和Ⅱc期患者由于诱导性多药化疗,其睾丸外分泌功能明显较差。所有患者均未出现腹膜后复发。在全部56例患者中,只有1例出现肺部复发(1.7%)。平均随访期为29个月。

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