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多囊卵巢疾病不孕患者卵巢表面的腹腔镜电凝术。

Laparoscopic electrocoagulation of the ovarian surface in infertile patients with polycystic ovarian disease.

作者信息

Naether O G, Fischer R, Weise H C, Geiger-Kötzler L, Delfs T, Rudolf K

机构信息

Institute for Hormone and Fertility Research, University of Hamburg, Germany.

出版信息

Fertil Steril. 1993 Jul;60(1):88-94. doi: 10.1016/s0015-0282(16)56042-7.

Abstract

OBJECTIVE

To assess the endocrinologic and clinical outcome after laparoscopic ovarian electrocautery because of polycystic reaction to ovarian stimulation in anovulatory infertility patients.

DESIGN

Between 1986 and 1989, 133 patients with polycystic ovarian disease underwent laparoscopic electrocoagulation of the ovarian surface in an outpatient clinic after conventional ovarian stimulation had led to polycystic reaction.

SETTING

All patients were referred to our outpatient clinic affiliated with the university hospital.

RESULTS

The reduction of androgen levels and normalization of cycle length were highly significant. The overall pregnancy rate was 70% (73 of 104), ranging from 27% in smokers to 94% in nonsmoking couples. In 26 second-look operations de novo adhesions were found in 26.9% of the patients.

CONCLUSION

Laparoscopic coagulation of the ovarian surface is an effective tool to reduce elevated androgen levels and to improve the intraovarian mechanism of selecting a dominant follicle. A postoperative complication may be adhesion formation.

摘要

目的

评估因无排卵性不孕症患者对卵巢刺激出现多囊反应而行腹腔镜卵巢电灼术后的内分泌及临床结局。

设计

1986年至1989年间,133例多囊卵巢疾病患者在常规卵巢刺激导致多囊反应后,于门诊接受了腹腔镜下卵巢表面电凝术。

地点

所有患者均被转诊至我们大学医院的门诊。

结果

雄激素水平降低及月经周期长度恢复正常非常显著。总体妊娠率为70%(104例中的73例),吸烟者为27%,非吸烟夫妇为94%。在26例二次探查手术中,26.9%的患者发现有新粘连形成。

结论

腹腔镜下卵巢表面电凝术是降低雄激素水平升高及改善卵巢内优势卵泡选择机制的有效手段。术后并发症可能是粘连形成。

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