Wilson L L, Dietrich J R
Department of Dairy and Animal Science, College of Agricultural Sciences, Pennsylvania State University, University Park 16802-3503.
J Am Vet Med Assoc. 1993 May 15;202(10):1730-3;discussion 1740-1.
The importance of extra-label drug use is discussed as this provision relates to special-fed veal production. Presently, there are 3 drugs approved and labeled for use in veal calves. Other medications and pharmaceuticals required to maintain and enhance calf health and well-being must be provided by consulting veterinarians under extra-label drug use provisions. Although special-fed veal has recently been reclassified as a minor use species (within Inter-Regional-4 designation), a sufficiently broad spectrum of safe and effective drugs will probably not be approved for use in veal calves within an acceptable and reasonable period. The use and practice of extra-label drug use provisions have apparently not represented a food safety hazard if the FSIS National Residue Program results are considered a measure of relative food safety. In 1988, the percentage of violative residues (based on all contaminants including antibiotics) was 3.3%; in 1991, this percentage was 0.24%. If existing extra-label drug use provisions were antagonistic with continuing efforts to enhance food safety, the percentage of violative residues would not have decreased. Perhaps not coincidentally, a comprehensive Veal Quality Assurance Educational Program (VQAEP) also was initiated in 1988. This industry-funded, industry-directed program is comparable to QAEP or total quality management programs conducted in other species and production systems. Over 80% of all US special-fed veal producers and others involved in the veal industry have participated in VQAEP seminars since 1988, with repeated attendance by many producers. Although the VQAEP has been effective, the goal of this and other programs must be zero violative residues.
本文讨论了超说明书用药的重要性,因为这一规定与特殊饲养的犊牛肉生产相关。目前,有3种药物被批准并标注可用于犊牛。维持和增强犊牛健康及福利所需的其他药物必须由咨询兽医根据超说明书用药规定提供。尽管特殊饲养的犊牛最近被重新归类为小用量动物品种(在区域间4指定范围内),但在可接受的合理时间内,可能不会批准足够广泛的安全有效药物用于犊牛。如果将美国食品安全检验局国家残留计划的结果视为相对食品安全的衡量标准,那么超说明书用药规定的使用和做法显然并未构成食品安全危害。1988年,违规残留的百分比(基于包括抗生素在内的所有污染物)为3.3%;1991年,这一百分比为0.24%。如果现有的超说明书用药规定与持续加强食品安全的努力相抵触,违规残留的百分比就不会下降。也许并非巧合的是,一项全面的犊牛肉质量保证教育计划(VQAEP)也于1988年启动。这个由行业资助、行业主导的计划类似于在其他动物品种和生产系统中开展的质量保证教育计划或全面质量管理计划。自1988年以来,超过80%的美国特殊饲养犊牛肉生产商及其他参与犊牛肉行业的人士参加了VQAEP研讨会,许多生产商还多次参加。尽管VQAEP取得了成效,但该计划及其他计划的目标必须是零违规残留。