Fujii Y, Tanaka H
Department of Anesthesiology, Toride Kyodo General Hospital.
Masui. 1993 May;42(5):694-7.
We studied the postoperative anti-emetic effects of low dose droperidol which was compared with that of metoclopramide in 60 gynecological patients. The effects at the third and 24th hours after surgery were evaluated by means of the nausea and vomiting score; 0 = none, 1 = discomfort, 2 = nausea, 3 = vomiting. The sores of postoperative nausea and vomiting within 3 hours after operation showed no significant difference between droperidol and metoclopramide groups (D: 0.2 +/- 0.4, M: 0.3 +/- 0.6). However, there was a significant difference between the two groups after 24 hours (D: 0.2 +/- 0.5, M: 0.8 +/- 1.0). We conclude that droperidol has a potent antiemetic effect that lasts after 24 hours.
我们研究了低剂量氟哌利多的术后止吐效果，并将其与甲氧氯普胺在60例妇科患者中的效果进行比较。通过恶心和呕吐评分评估术后第3小时和第24小时的效果；0 = 无，1 = 不适，2 = 恶心，3 = 呕吐。术后3小时内，氟哌利多组和甲氧氯普胺组术后恶心和呕吐评分无显著差异（氟哌利多组：0.2±0.4，甲氧氯普胺组：0.3±0.6）。然而，24小时后两组之间存在显著差异（氟哌利多组：0.2±0.5，甲氧氯普胺组：0.8±1.0）。我们得出结论，氟哌利多具有强效止吐作用，且在24小时后仍持续存在。
