Issues and challenges in clinical nursing research.

In this article, issues encountered that are problematic in conducting research in clinical settings are discussed along with potential solutions. Subject accrual, compatibility of the research protocol with day-to-day operation of the clinical site, gaining cooperation from groups of health professionals, and obtaining required approvals are the most common problems encountered. Overcoming these problems does not mean the elimination of them; awareness and acknowledgement of these problems in the planning process will minimize the negative influence they may have on the study.