Knopp M V, Hess T, Bachert P, Ende G, Junkermann H, Hesterkamp T, van Kaick G
Forschungsschwerpunkt Radiologische Diagnostik und Therapie, Deutsches Krebsforschungszentrum, Heidelberg.
Radiologe. 1993 May;33(5):300-7.
Conservative therapeutic concepts with initial chemotherapy for patients with breast cancer represent a challenge to non-invasive techniques for monitoring response to therapy. Experimental magnetic resonance spectroscopy studies have been able to show exemplary applications for therapy monitoring of breast cancer patients. The characteristic phosphomonoester resonances and their changes during therapy are possible clinical parameters. The additional information which can be obtained from proton and carbon spectroscopy increases the amount of detectable metabolites. On-going studies are investigating clinical applications of multinuclear spectroscopic studies in patients with breast cancer.
对于乳腺癌患者采用初始化疗的保守治疗理念，对监测治疗反应的非侵入性技术构成了挑战。实验性磁共振波谱研究已能够展示在乳腺癌患者治疗监测中的典型应用。特征性的磷酸单酯共振及其在治疗过程中的变化是可能的临床参数。从质子和碳谱中可获得的额外信息增加了可检测代谢物的数量。正在进行的研究正在调查多核波谱研究在乳腺癌患者中的临床应用。
