透析相关性淀粉样变性

Dialysis-associated amyloidosis.

作者信息

Sethi D

机构信息

Charing Cross and Westminster Medical School, London, UK.

出版信息

Ren Fail. 1993;15(3):349-51. doi: 10.3109/08860229309054943.

DOI:10.3109/08860229309054943

PMID:8516489

Abstract

Dialysis arthropathy (DA) and carpal tunnel syndrome are debilitating complications caused by dialysis-associated amyloidosis. They arise after several years of hemodialysis with cuprophane and their onset can be delayed with the use of high-flux dialysis. Serum C-reactive protein is elevated in patients with dialysis arthropathy, indicative of inflammatory processes. X-rays show periarticular bone cysts and erosive spondyloarthropathy. High-flux dialysis improves DA, but transplantation remains the best treatment.

摘要

透析性关节病（DA）和腕管综合征是由透析相关性淀粉样变性引起的使人衰弱的并发症。它们在使用铜仿膜进行数年血液透析后出现，使用高通量透析可延迟其发病。透析性关节病患者的血清C反应蛋白升高，提示存在炎症过程。X线显示关节周围骨囊肿和侵蚀性脊椎关节病。高通量透析可改善透析性关节病，但移植仍是最佳治疗方法。