肢体先天性发育不全畸形的流行病学研究
An epidemiological study of congenital reduction deformities of the limbs.
作者信息
Smith E S, Dafoe C S, Miller J R, Banister P
出版信息
Br J Prev Soc Med. 1977 Mar;31(1):39-41. doi: 10.1136/jech.31.1.39.
A retrospective study that was undertaken to determine why more infants had been born with congenital reduction deformities of the limbs is reported. The increase was detected by the Congenital Anomaly Surveillance System in 1969. Ninety-three infants born in Alberta and British Columbia in 1969-71 with congenital reduction deformities were matched with 93 normal infants and 93 infants with congenital malformations of a different type. The mothers of all infants were interviewed to obtain information on factors thought relevant to the establishment of a causal relationship. Although there were some significant differences between cases and normaland/or abnormal controls, this number of differences might have been expected by chance. No single causal relationship was established.
据报道，一项回顾性研究旨在确定为何有更多婴儿出生时患有先天性肢体短小畸形。1969年，先天性异常监测系统发现了这一增长情况。对1969 - 1971年在艾伯塔省和不列颠哥伦比亚省出生的93名患有先天性肢体短小畸形的婴儿，与93名正常婴儿以及93名患有其他类型先天性畸形的婴儿进行了匹配。对所有婴儿的母亲进行了访谈，以获取与建立因果关系相关因素的信息。尽管病例组与正常组和/或异常对照组之间存在一些显著差异，但这些差异数量有可能是偶然出现的。未确立单一的因果关系。
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