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[奥地利5个联邦州农业学校的危险因素筛查]

[Screening for risk factors in agricultural schools of 5 Austrian federal counties ].

作者信息

Yang Q, Fischer W, Virgolini I, Seyfried H, Widhalm K, Sinzinger H

机构信息

Wilhelm Auerswald-Atheroskleroseforschungsgruppe (ASF), Wien.

出版信息

Wien Med Wochenschr. 1993;143(6):134-41.

PMID:8517064
Abstract

While screening activities have already been performed in a wide range in adults in Austria, extensive investigations in children and juveniles have so far only been done in a very limited number. In 1094 out of 1732 juveniles attending agricultural schools all lipid parameters were fully documented and thus could be evaluated. On an average, the total cholesterol (169 mg/dl) was too high; the worst findings for lipid parameters cholesterol, HDL-cholesterol, triglycerides, apolipoprotein-A1 were found in pupils of Burgenland. The cholesterol/HDL-cholesterol ratio in Burgenland was significantly (p < 0.01) higher than in Lower Austria. Female participants had a higher total cholesterol, HDL-cholesterol, and apolipoprotein-A1, but lower triglycerides and also lower blood pressure. Juveniles with a positive family history showed lower total cholesterol, but higher triglycerides as well as HDL-cholesterol. In heavy smokers, but also in occasional smokers, a lower total cholesterol, but decreased HDL-cholesterol and apolipoprotein-A1 and increased triglycerides were found. These findings underline the high prevalence of hypercholesterolemia in juveniles justifying screening activities and possibly therapeutic intervention at this young age.

摘要

虽然奥地利已经在成年人中广泛开展了筛查活动,但迄今为止,针对儿童和青少年的广泛调查数量非常有限。在1732名就读农业学校的青少年中,有1094人的所有血脂参数都有完整记录,因此可以进行评估。平均而言,总胆固醇(169毫克/分升)过高;布尔根兰州的学生在胆固醇、高密度脂蛋白胆固醇、甘油三酯、载脂蛋白A1等血脂参数方面的检测结果最差。布尔根兰州的胆固醇/高密度脂蛋白胆固醇比值显著高于下奥地利州(p < 0.01)。女性参与者的总胆固醇、高密度脂蛋白胆固醇和载脂蛋白A1较高,但甘油三酯较低,血压也较低。有家族病史的青少年总胆固醇较低,但甘油三酯和高密度脂蛋白胆固醇较高。在重度吸烟者以及偶尔吸烟者中,总胆固醇较低,但高密度脂蛋白胆固醇和载脂蛋白A1降低,甘油三酯升高。这些发现凸显了青少年高胆固醇血症的高患病率,证明在这个年轻年龄段开展筛查活动并可能进行治疗干预是合理的。

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