Chéry-Croze S, Collet L, Morgon A
URA CNRS 1447, Hôpital E. Herriot, Lyon, France.
Acta Otolaryngol. 1993 May;113(3):285-90. doi: 10.3109/00016489309135810.
A possible role of the efferent system in the mechanisms of tinnitus generation has been put forward by several authors. A simple method for studying the functioning of this system is to compare the amplitudes of otoemissions with and without mild contralateral stimulation. In a recent communication, Veuillet et al. (1991) reported that, on the side of tinnitus, the efferent system of patients suffering from unilateral tinnitus seems to be less efficient than on the other side. The results presented here correspond to those obtained in the very first tinnitus patients submitted to a research protocol exploring systematically the efferent system. When possible, the effectiveness was tested in two ways: globally, using evoked otoacoustic emissions (EOAEs) and, very precisely in the frequency zone of the tinnitus, using cubic distortion product 2f1-f2. Preliminary results obtained in bilateral and unilateral tinnitus sufferers show that a majority of them exhibits, at least in the proximity of the tinnitus, a lack of effectiveness of the efferent system. In some of them, instead of the suppressive effect, an increasing one was even observed.
几位作者提出了传出系统在耳鸣产生机制中的可能作用。研究该系统功能的一种简单方法是比较有和没有轻度对侧刺激时耳声发射的幅度。在最近的一篇通讯中,Veuillet等人(1991年)报告说,在耳鸣一侧,单侧耳鸣患者的传出系统似乎比另一侧效率更低。此处呈现的结果与在首批接受系统探索传出系统研究方案的耳鸣患者中获得的结果一致。在可能的情况下,通过两种方式测试有效性:整体上,使用诱发耳声发射(EOAE);非常精确地在耳鸣的频率区域,使用立方畸变产物2f1-f2。在双侧和单侧耳鸣患者中获得的初步结果表明,他们中的大多数人至少在耳鸣附近表现出传出系统缺乏有效性。在其中一些患者中,甚至观察到的不是抑制作用,而是增强作用。