Grimm W, Flores B F, Marchlinski F E
Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia.
Am J Cardiol. 1993 Jun 15;71(16):1415-8. doi: 10.1016/0002-9149(93)90602-9.
During a follow-up of 24 +/- 20 months after treatment with an implantable cardioverter-defibrillator (ICD), 101 of 241 patients (42%) received > or = 1 spontaneous ICD shocks with documentation of the rhythm leading to shock by Holter or telemetry monitoring or stored electrograms by the device. Sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) was documented in 67 of the 101 patients (66%) with electrocardiographically documented shocks, nonsustained VT in 4 patients (4%), supraventricular tachyarrhythmias in 41 patients (41%), and normal sinus or pacemaker rhythm in 10 patients (10%). No, mild (palpitations and/or mild dizziness) and severe symptoms (presyncope/syncope) preceded spontaneous ICD shocks in 20 (30%), 33 (49%) and 27 (42%) of the 67 patients, respectively, with electrocardiographically documented VT or VF, and in 23 (56%), 16 (39%) and 1 (2%) of the 41 patients, respectively, with electrocardiographically documented supraventricular tachyarrhythmias. Three of the 4 patients with nonsustained VT had mild symptoms, and 1 patient with nonsustained VT had presyncope. None of the 10 patients with spurious discharges during normal sinus or pacemaker rhythm had symptoms preceding the ICD shocks. It is concluded that (1) most patients with either electrocardiographically documented VT/VF or a non-VT/VF rhythm preceding spontaneous ICD shocks have no or mild symptoms preceding the shock, and (2) severe symptoms preceding ICD shocks suggest sustained VT or VF as the underlying rhythm, although severe symptoms rarely occur in patients with supraventricular tachyarrhythmias or nonsustained VT.
在植入式心脏复律除颤器(ICD)治疗后24±20个月的随访期间,241例患者中有101例(42%)接受了≥1次自发ICD电击,通过动态心电图或遥测监测记录了导致电击的心律,或通过设备存储的心电图记录。在101例有心电图记录电击的患者中,67例(66%)记录到持续性室性心动过速(VT)或心室颤动(VF),4例(4%)为非持续性VT,41例(41%)为室上性快速心律失常,10例(10%)为正常窦性或起搏器心律。在67例有心电图记录VT或VF的患者中,分别有20例(30%)、33例(49%)和27例(42%)在自发ICD电击前无、有轻度症状(心悸和/或轻度头晕)和严重症状(先兆晕厥/晕厥);在41例有心电图记录室上性快速心律失常的患者中,分别有23例(56%)、16例(39%)和1例(2%)在自发ICD电击前有上述情况。4例非持续性VT患者中有3例有轻度症状,1例有先兆晕厥。10例在正常窦性或起搏器心律时有假性放电的患者在ICD电击前均无症状。结论为:(1)大多数心电图记录为VT/VF或自发ICD电击前为非VT/VF心律的患者在电击前无或有轻度症状;(2)ICD电击前的严重症状提示潜在心律为持续性VT或VF,尽管严重症状在室上性快速心律失常或非持续性VT患者中很少出现。