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促红细胞生成素免疫测定中的不可靠性:使用一种检测试剂盒时的异常估计值。

Unreliability in immunoassays of erythropoietin: anomalous estimates with an assay kit.

作者信息

Bechensteen A G, Lappin T R, Marsden J, Muggleston D, Cotes P M

机构信息

Department of Paediatrics, Ulleval Hospital, Oslo, Norway.

出版信息

Br J Haematol. 1993 Apr;83(4):663-4. doi: 10.1111/j.1365-2141.1993.tb04708.x.

Abstract

We report the finding of inappropriately high estimates of erythropoietin (Epo) in 11% of serum samples tested by one commercial assay kit. These estimates were not confirmed when the same samples were tested independently in four other systems for the immunoassay of Epo. As yet no explanation has been found to account for the anomalously high estimates.

摘要

我们报告了一个发现,即使用一种商业检测试剂盒检测的血清样本中,有11%的促红细胞生成素(Epo)估计值过高。当在其他四个独立的Epo免疫检测系统中对相同样本进行检测时,这些估计值并未得到证实。目前尚未找到解释这些异常高估计值的原因。

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