Motz W, Vogt M, Strauer B E
Abteilung für Kardiologie, Pneumologie und Angiologie, Heinrich-Heine-Universität, Düsseldorf.
Clin Investig. 1993;71(5 Suppl):S42-5. doi: 10.1007/BF00180075.
In arterial hypertension left ventricular hypertrophy comprises myocyte hypertrophy, interstitial fibrosis and structural alterations of the coronary microcirculation. This leads to an impairment of diastolic function of the left ventricle and coronary flow reserve despite normal epicardial arteries. Consequently, antihypertensive treatment should aim at [13] reversing myocyte hypertrophy, [14] restoring myocardial structure and [8] improving coronary flow reserve along with blood pressure normalization.
在动脉高血压中，左心室肥厚包括心肌细胞肥大、间质纤维化以及冠状动脉微循环的结构改变。尽管心外膜动脉正常，但这会导致左心室舒张功能受损以及冠状动脉血流储备降低。因此，抗高血压治疗应旨在[13]逆转心肌细胞肥大，[14]恢复心肌结构，以及[8]在血压正常化的同时改善冠状动脉血流储备。
