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垂体中内啡肽(具有吗啡样药理活性的肽)的分布。

Distribution of endorphins (peptides with morphine-like pharmacological activity) in pituitary.

作者信息

Ross M, Dingledine R, Cox B M, Goldstein A

出版信息

Brain Res. 1977 Apr 1;124(3):523-32. doi: 10.1016/0006-8993(77)90951-9.

Abstract

Endorphin was found in the pituitary gland of rat, sheep, pig, cow and man. In bovine pituitary, highest concentrations have been found in that part of the posterior lobe containing the pars intermedia, although endorphin was also present in the pars distalis. Analysis by gel filtration and adsorption chromatography suggested that the major endorphins from rat, pig and cow pituitary were similar, with apparent molecular weights in the range 3000-3500 daltons.

摘要

在大鼠、绵羊、猪、牛和人的垂体中发现了内啡肽。在牛垂体中,虽然远侧部也存在内啡肽,但在后叶含有中间部的那部分中发现了最高浓度。凝胶过滤和吸附色谱分析表明,大鼠、猪和牛垂体中的主要内啡肽相似,表观分子量在3000 - 3500道尔顿范围内。

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