Shabadash S A, Zelikina T I
Izv Akad Nauk Ser Biol. 1993 May-Jun(3):410-25.
Studies on the circumanal skin of a three-week-old puppy have shown that, contrary to the adult dogs, sebaceous glands are absent here (although they are well-developed in other skin sites of the puppy). Hepatoid glands accompany every hair follicle; they differ considerably from hepatoid glands of adult dogs. Hepatoid circumanal glands of the three-week old puppy are represented by two histological varieties of this glandular type which are capable of producing hydrophobic lipids, are rather poor in protein, and do not possess cysts--while in adult dogs they are represented by only one variety incapable of synthesizing lipids, extremely rich in protein, possessing numerous cysts. Discussion concerns histogenesis, distribution, and function of certain hepatoid gland varieties which were first described by the authors in their previous publication.