Lemire I
Centre hospitalier régional de Lanaudière, Joliette, Québec.
Can J Psychiatry. 1993 May;38(4):277-84. doi: 10.1177/070674379303800410.
Kleine-Levin syndrome is a characterized by a periodic hypersomnia crisis as well as dietary and variable significant psychic symptoms. Its rarity makes its definition and study complex. Many etiologies have been considered, especially regarding a hypothalamic dysfunction. Physiological, radiologic, anatomical and polysomnographic studies have not shown clearly conclusive results, but the syndrome appears to be related to affective disorders. This hypothesis is supported by the findings of a positive therapeutic response to lithium. However, we are interested in the related psychological factors, whether they are primary or secondary. A clinical case illustrates these factors, and a basic neuropsychiatric intervention concept is proposed.
克莱恩-莱文综合征的特征是周期性嗜睡发作以及饮食和多种明显的精神症状。其罕见性使得对它的定义和研究变得复杂。人们考虑了许多病因，尤其是关于下丘脑功能障碍的病因。生理学、放射学、解剖学和多导睡眠图研究并未得出明确的结论性结果，但该综合征似乎与情感障碍有关。锂治疗有积极反应这一发现支持了这一假说。然而，我们关注与之相关的心理因素，无论它们是原发性的还是继发性的。一个临床病例说明了这些因素，并提出了一个基本的神经精神干预概念。
