Bradley M J, Spencer P A, Alexander L, Milner G R
Medical Imaging Department, District General Hospital, Rotherham, Oakwood.
Clin Radiol. 1993 Jun;47(6):399-402. doi: 10.1016/s0009-9260(05)81060-8.
This prospective trial was organized to evaluate further the role of colour flow Doppler ultrasound techniques in the diagnosis of deep vein thrombosis (DVT) with particular reference to the isolated calf lesion. In 100 patients ultrasound was compared against the recognized gold standard of ascending venography. Fifty venograms were positive for DVT compared with 49 on ultrasound, a sensitivity of 98%. The specificity of ultrasound for DVT in the 50 patients without DVT on venography was 100%. Forty-five venograms demonstrated calf thrombus with varying proximal extent. Sixteen proved to be isolated calf lesions and these were all identified by ultrasound (100% sensitivity and specificity respectively for isolated calf DVT). In five of these isolated calf thrombus cases, results suggested that ultrasound better diagnosed the presence of thrombus. Ultrasound diagnosed significant pathology in 13 of the normal venogram patients giving an overall diagnostic yield of 62% as compared to 50% at venography.
这项前瞻性试验旨在进一步评估彩色多普勒超声技术在诊断深静脉血栓形成（DVT）中的作用，特别是针对孤立性小腿病变。对100例患者进行了超声检查，并与公认的上行静脉造影金标准进行了比较。50例静脉造影显示DVT阳性，而超声检查发现49例，敏感性为98%。在静脉造影未发现DVT的50例患者中，超声对DVT的特异性为100%。45例静脉造影显示小腿血栓，近端范围各不相同。其中16例被证明是孤立性小腿病变，这些均被超声检出（孤立性小腿DVT的敏感性和特异性分别为100%）。在这些孤立性小腿血栓病例中的5例中，结果表明超声能更好地诊断血栓的存在。超声在13例静脉造影正常的患者中诊断出显著病变，总体诊断率为62%，而静脉造影的诊断率为50%。
