Ohira T, Watanabe Y, Mezaki T, Machii K, Kuzuhara S
Department of Neurology, Matsusaka Central General Hospital.
Rinsho Shinkeigaku. 1995 Jun;35(6):643-7.
We report a rare case of pyomyositis in a 28-year-old Japanese woman who was not immunocompromised. She was admitted because of high fever, sore throat, and severe tenderness and swelling of the right calf. Redness, swelling, and tenderness indicated presence of acute inflammation in the calf. CT of the lower extremities demonstrated low density areas in the right soleus muscle and surrounding fascia with marked swelling, which were of high signal on T2 weighted images of MRI. There was no finding of abscess formation. A tentative clinical diagnosis of acute pyomyositis was made, and antibiotics therapy with a combination of fosfomycin and sulbactam/cefoperazone was started although the arterial blood culture was negative for bacteria. Associated acute tonsilitis was the most probable focus of pyomyositis. Antibiotics relieved her symptoms, and the inflammation subsided in several weeks. No surgical procedure was necessary. MRI taken tree weeks after the onset demonstrated abscess formation between the soleus and gastrocnemius muscles. Slight high intensity indicating scar formation remained in the area of the former abscess six weeks after the onset. MRI was very useful not only in making the early diagnosis but also in the follow-up of pyomyositis.
我们报告一例28岁未免疫功能低下的日本女性患脓性肌炎的罕见病例。她因高热、咽痛以及右小腿严重压痛和肿胀入院。小腿部的发红、肿胀及压痛表明存在急性炎症。下肢CT显示右比目鱼肌及周围筋膜有低密度区伴明显肿胀,在MRI的T2加权像上呈高信号。未发现脓肿形成。尽管动脉血细菌培养阴性,但仍初步临床诊断为急性脓性肌炎,并开始使用磷霉素联合舒巴坦/头孢哌酮进行抗生素治疗。伴发的急性扁桃体炎很可能是脓性肌炎的病灶。抗生素缓解了她的症状,炎症在数周内消退。无需进行外科手术。发病三周后进行的MRI显示比目鱼肌和腓肠肌之间形成脓肿。发病六周后,原脓肿部位仍有轻微高强度信号,提示瘢痕形成。MRI不仅对脓性肌炎的早期诊断非常有用,而且对其随访也很有帮助。