Meyer M A, McClaughry P
Department of Nuclear Medicine, University of Tennessee Medical Center, Knoxville, USA.
Clin Nucl Med. 1995 Sep;20(9):767-9. doi: 10.1097/00003072-199509000-00002.
A 52-year-old man with metastatic poorly differentiated bronchogenic carcinoma and serum calcium levels as high as 14.6 had intense Tc-99m MDP uptake found throughout the stomach wall on SPECT imaging. FDG uptake assessed by PET imaging was not elevated in the stomach, whereas multiple hyper-metabolic tumor foci could be found throughout the body. Three months later, when calcium levels normalized, no Tc-99m MDP uptake was found in the stomach despite persistence of neoplastic lesions elsewhere. This case study indicates that gastric MDP uptake in patients with malignancy related hypercalcemia can be reversible and not necessarily indicative of neoplastic infiltration.
一名52岁男性，患有转移性低分化支气管癌，血清钙水平高达14.6，在SPECT成像中发现整个胃壁有强烈的锝-99m亚甲基二膦酸盐（Tc-99m MDP）摄取。PET成像评估的胃内氟代脱氧葡萄糖（FDG）摄取未升高，而全身可发现多个高代谢肿瘤病灶。三个月后，当钙水平恢复正常时，尽管其他部位仍存在肿瘤病变，但胃内未发现Tc-99m MDP摄取。本病例研究表明，恶性肿瘤相关高钙血症患者的胃内MDP摄取可能是可逆的，不一定提示肿瘤浸润。
