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一种编码来自寄生线虫犬弓首蛔虫核糖体蛋白L3的互补DNA。

A cDNA encoding ribosomal protein L3 from the parasitic nematode Toxocara canis.

作者信息

Moore J, Todorova V, Kennedy M W

机构信息

Wellcome Laboratories for Experimental Parasitology, University of Glasgow, UK.

出版信息

Gene. 1995 Nov 20;165(2):239-42. doi: 10.1016/0378-1119(95)00565-n.

DOI:10.1016/0378-1119(95)00565-n
PMID:8522183
Abstract

A cDNA encoding the ribosomal (r) protein L3 of the parasitic nematode Toxocara canis was isolated from a library constructed from mRNA of the infective larval stage. The encoded protein has a high degree of similarity to r-protein L3 from other organisms, including mammals, yeast, plants and bacteria. The mRNA encoding r-protein L3 is derived from a single-copy gene, and experimental evidence would suggest that it contains the pan-nematode splice leader sequence at its 5' end and that the gene is interrupted by at least three introns.

摘要

从感染性幼虫阶段的mRNA构建的文库中分离出一种编码犬弓首线虫寄生线虫核糖体(r)蛋白L3的cDNA。编码的蛋白质与来自其他生物(包括哺乳动物、酵母、植物和细菌)的r蛋白L3具有高度相似性。编码r蛋白L3的mRNA来源于一个单拷贝基因,实验证据表明它在其5'端含有泛线虫剪接前导序列,并且该基因被至少三个内含子中断。

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引用本文的文献

1
Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy.通过表达序列标签策略从犬弓首蛔虫感染性幼虫阶段鉴定大量表达的新基因和保守基因。
Infect Immun. 1999 Sep;67(9):4771-9. doi: 10.1128/IAI.67.9.4771-4779.1999.