一种编码来自寄生线虫犬弓首蛔虫核糖体蛋白L3的互补DNA。

A cDNA encoding ribosomal protein L3 from the parasitic nematode Toxocara canis.

作者信息

Moore J, Todorova V, Kennedy M W

机构信息

Wellcome Laboratories for Experimental Parasitology, University of Glasgow, UK.

出版信息

Gene. 1995 Nov 20;165(2):239-42. doi: 10.1016/0378-1119(95)00565-n.

DOI:10.1016/0378-1119(95)00565-n

PMID:8522183

Abstract

A cDNA encoding the ribosomal (r) protein L3 of the parasitic nematode Toxocara canis was isolated from a library constructed from mRNA of the infective larval stage. The encoded protein has a high degree of similarity to r-protein L3 from other organisms, including mammals, yeast, plants and bacteria. The mRNA encoding r-protein L3 is derived from a single-copy gene, and experimental evidence would suggest that it contains the pan-nematode splice leader sequence at its 5' end and that the gene is interrupted by at least three introns.

摘要

从感染性幼虫阶段的mRNA构建的文库中分离出一种编码犬弓首线虫寄生线虫核糖体（r）蛋白L3的cDNA。编码的蛋白质与来自其他生物（包括哺乳动物、酵母、植物和细菌）的r蛋白L3具有高度相似性。编码r蛋白L3的mRNA来源于一个单拷贝基因，实验证据表明它在其5'端含有泛线虫剪接前导序列，并且该基因被至少三个内含子中断。