Pascual A, García I, Ramirez de Arellano E, Perea E J
Department of Microbiology, School of Medicine, Sevilla, Spain.
J Antimicrob Chemother. 1995 Aug;36(2):425-30. doi: 10.1093/jac/36.2.425.
The activity of sparfloxacin on Staphylococcus epidermidis biofilms on different plastic catheters was evaluated. Sparfloxacin showed high bactericidal activity against S. epidermidis biofilms on Vialon and polyvinylchloride catheters. The combination of sparfloxacin with amikacin or rifampicin significantly increased its activity against bacterial biofilms on polyurethane and Teflon catheters.