Llopis J, Romero J A, Gutiérrez R, Alvarez R, Talbot R, Vendrell J R, Barranco M A, Carretero P
Service d'Urologie et de transplantation rénale, Université de Barcelone, Hospital Clinic i Provincial Barcelona, Espagne.
J Urol (Paris). 1995;101(2):104-6.
The authors report two cases of priapism of more than six hours, following intracavernous injection of 15 and 10 mcg PgE1 respectively, in six patients with impotence after radical cystoprostatectomy. Bearing in mind the proven safety of intracavernous injection of PgE1 in the treatment and diagnosis of erectile dysfunction, such a proportion of priapism in this group of patients has called our attention. It is probably due to an increased in the PgE1 intracavernous metabolism, due to the ligation of the penile venous drainage during surgery.
作者报告了6例根治性膀胱前列腺切除术后阳痿患者，分别经海绵体内注射15微克和10微克前列腺素E1（PgE1）后发生持续超过6小时的阴茎异常勃起的2例病例。鉴于海绵体内注射PgE1在勃起功能障碍治疗和诊断中的安全性已得到证实，该组患者中如此比例的阴茎异常勃起引起了我们的关注。这可能是由于手术期间阴茎静脉引流结扎导致海绵体内PgE1代谢增加所致。
