Hoshi T, Saito Y
Contrib Nephrol. 1977;6:52-60. doi: 10.1159/000399752.
Microelectrode studies were performed to examine the specificity of the electrogenic sugar transport by Triturus proximal tubule. Two types of carriers could be distinguished, one having an affinity for D-mannose but not for D-xylose (M type), and the other having the reverse characteristics (X type). D-Glucose and alpha-methyl-D-glucoside had a relatively high affinity for both types of carriers, but D-galactose, D-fructose, 3-O-methyl-D-glucose, D-mannitol and L-glucose had no affinity for them. The observed structural requirements of renal sugar transport were different from and stricter than those of intestinal sugar transport observed in the same animal.
进行微电极研究以检测蝾螈近端小管电生性糖转运的特异性。可区分出两种类型的载体，一种对D-甘露糖有亲和力而对D-木糖没有（M型），另一种具有相反的特性（X型）。D-葡萄糖和α-甲基-D-葡萄糖苷对两种类型的载体都有相对较高的亲和力，但D-半乳糖、D-果糖、3-O-甲基-D-葡萄糖、D-甘露醇和L-葡萄糖对它们没有亲和力。观察到的肾脏糖转运的结构要求与在同一动物中观察到的肠道糖转运的结构要求不同且更严格。
