获得性特发性全身性无汗症：临床表现及组织化学研究

Acquired idiopathic generalized anhidrosis: clinical manifestations and histochemical studies.

作者信息

Ando Y, Fujii S, Sakashita N, Uchino M, Ando M

机构信息

First Department of Internal Medicine, Kumamoto University School of Medicine, Japan.

出版信息

J Neurol Sci. 1995 Sep;132(1):80-3. doi: 10.1016/0022-510x(95)00125-l.

DOI:10.1016/0022-510x(95)00125-l

PMID:8523036

Abstract

A 40-year-old male developed complete absence of sweating except for slight sweating in the axillar region. Histopathologic examination of the skin revealed lymphocytes infiltration around the sweat glands and coarse and irregular arrangement of the eccrine glands. Immunohistochemical staining using anti-CD3, CD4, and CD8 antibodies revealed that CD3 positive cells were dominant in the lesion. After intensive glucocorticoid treatment, generalized sweating was almost completely recovered.

摘要

一名40岁男性除腋窝区域有轻微出汗外，全身无汗。皮肤组织病理学检查显示汗腺周围有淋巴细胞浸润，小汗腺排列粗糙且不规则。使用抗CD3、CD4和CD8抗体进行免疫组织化学染色显示，病变中CD3阳性细胞占主导。经过强化糖皮质激素治疗后，全身出汗几乎完全恢复。