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使用间碘苄胍(MIBG)对胸腺原发性类癌肿瘤进行术前诊断。

Presurgical diagnosis of a primary carcinoid tumor of the thymus with MIBG.

作者信息

Hirano T, Otake H, Watanabe N, Oriuchi N, Zennyouji A, Fukuda T, Endo K

机构信息

Department of Nuclear Medicine, Gunma University School of Medicine, Japan.

出版信息

J Nucl Med. 1995 Dec;36(12):2243-5.

PMID:8523113
Abstract

A primary carcinoid tumor of the thymus showing ectopic ACTH syndrome was evaluated scintigraphically with four radiopharmaceuticals and a fluorescence method. Iodine-123-MIBG and 201Tl-Cl scintigraphy clearly demonstrated the tumor. Gallium-67-citrate and 99mTc(V)-DMSA showed no tumor uptake. The fluorescence method confirmed numerous storage granules of norepinephrine. Iodine-123-MIBG scintigraphy could be useful in the presurgical diagnosis of carcinoid tumors of the thymus.

摘要

对一例表现为异位促肾上腺皮质激素(ACTH)综合征的胸腺原发性类癌肿瘤,采用四种放射性药物和一种荧光方法进行了闪烁显像评估。碘-123-间碘苄胍(MIBG)和铊-201(201Tl)-氯化物闪烁显像清晰显示了肿瘤。枸橼酸镓-67和锝-99m(99mTc)(V)-二巯基丁二酸(DMSA)未显示肿瘤摄取。荧光方法证实了去甲肾上腺素的大量储存颗粒。碘-123-MIBG闪烁显像可能有助于胸腺类癌肿瘤的术前诊断。

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