Uceda J E, Laos C A, Kolni H W, Klein A M
Department of Pediatric Surgery, Methodist Medical Center, Dallas, TX, USA.
J Pediatr Surg. 1995 Sep;30(9):1314-6. doi: 10.1016/0022-3468(95)90493-x.
Seventeen infants with a very low birth weight (VLBW) and spontaneous, non-necrotizing enterocolitis (NEC), intestinal perforations are presented; 14 of them were seen in the past 3 years. A comparison with 16 surgically treated NEC infants (< 1,000 g) is provided. At our institution, the yearly survival of VLBW infants increased from 54% to 90% over the past 6 years. All 17 non-NEC patients were operated on, and 15 (88.2%) survived. Ileal perforations were observed frequently. Initial enterostomies were followed by reanastomosis at an average age of 3 months. A 22.6-month follow-up was attained for all survivors. Non-NEC intestinal perforations in tiny neonates are increasing and constitute a challenging but treatable group. The improving survival rate of VLBW infants will probably be accompanied by a variety of complications.
本文报告了17例极低出生体重（VLBW）且患有自发性、非坏死性小肠结肠炎（NEC）并伴有肠穿孔的婴儿；其中14例是在过去3年中发现的。同时提供了与16例接受手术治疗的NEC婴儿（<1000g）的对比情况。在我们机构，极低出生体重婴儿的年生存率在过去6年中从54%提高到了90%。所有17例非NEC患者均接受了手术，其中15例（88.2%）存活。回肠穿孔较为常见。最初进行肠造口术，平均在3个月大时进行再次吻合。所有幸存者均获得了22.6个月的随访。微小新生儿的非NEC肠穿孔病例正在增加，这是一个具有挑战性但可治疗的群体。极低出生体重婴儿生存率的提高可能会伴随着各种并发症。
