Strauss B L, Matthews M J, Cohen M H, Simon R, Tejada F
Chest. 1977 May;71(5):607-11. doi: 10.1378/chest.71.5.607.
Cardiac metastases from bronchogenic carcinoma are not commonly diagnosed prior to death. This study isolates factors associated wtih the development of cardiac involvement. Four hundred eighteen consecutive patients with lung cancer who had autopsies were studied. Twenty-five percent of these patients had cardiac involvement. Factors associated with cardiac metastases were (1) histologic cell type of the tumor, (2) aggressive therapy, (3) extent of disease, and (4) tumor differentiation. The presence of cardiac metatases was not related to the length of survival. Clinical signs of cardiac involvement included an enlarging heart on the chest x-ray film, development of congestive heart failure, or electrocardiographic changes. Suspicion of cardiac metastases in high-risk individuals, prompt diagnostic evaluation, and rapid institution of therapy may improve the outlook for many patients, since reaccumulation of fluid was generally slow.
支气管源性癌的心脏转移在死亡前通常不易被诊断出来。本研究分离出与心脏受累发展相关的因素。对418例连续进行尸检的肺癌患者进行了研究。这些患者中有25%出现了心脏受累。与心脏转移相关的因素有：（1）肿瘤的组织学细胞类型；（2）积极治疗；（3）疾病范围；（4）肿瘤分化程度。心脏转移的存在与生存时间无关。心脏受累的临床体征包括胸部X光片上心脏增大、充血性心力衰竭的发生或心电图改变。对高危个体怀疑有心脏转移时，及时进行诊断评估并迅速开始治疗可能会改善许多患者的预后，因为液体的再次积聚通常较为缓慢。
