[123I-β-甲基-碘代苯基十五烷酸和201Tl心肌单光子发射计算机断层显像在不稳定型心绞痛中的诊断价值]
[Diagnostic usefulness of myocardial SPECT with 123I-beta-methyl-iodophenyl pentadecanoic acid and 201Tl in unstable angina].
作者信息
Nakazawa Y, Tahara H, Suyama H, Kakio T, Ohue Y, Goto Y, Inoue K, Yamamoto Y, Nakamura N, Masui K
机构信息
Department of Cardiology, Matsue Red Cross Hospital, Japan.
出版信息
Kaku Igaku. 1995 Sep;32(9):953-8.
The purpose of this study is whether 123I-BMIPP detects a culprit lesion in patients with unstable angina. Twenty-six patients with unstable angina underwent 123I-BMIPP (BMIPP) and 201Tl (Tl) imaging at rest. BMIPP image was compared with Tl imaging. BMIPP imaging revealed defects or low uptake corresponding to myocardial ischemic areas predicted by coronary angiography in 19 (73.1%) of 26 patients. Tl imaging showed defects or low uptake corresponding to coronary angiographic findings in 14 (53.8%). BMIPP demonstrated significantly less uptake than Tl (p = 0.001). Severity of reduced BMIPP activity was greater than that of Tl (p < 0.001). We concluded that BMIPP imaging was excellent to detecting of culprit lesions in patients with unstable angina. BMIPP SPECT is a sensitive method for detecting myocardium exposed to transient schemia that cannot be detected by Tl imaging.
本研究的目的是探讨¹²³I-苄基十五烷酸（BMIPP）能否检测出不稳定型心绞痛患者的罪犯病变。26例不稳定型心绞痛患者在静息状态下接受了¹²³I-苄基十五烷酸（BMIPP）和²⁰¹铊（Tl）显像。将BMIPP图像与Tl图像进行比较。BMIPP显像显示，26例患者中有19例（73.1%）出现与冠状动脉造影预测的心肌缺血区域相对应的缺损或摄取减低。Tl显像显示，14例（53.8%）出现与冠状动脉造影结果相对应的缺损或摄取减低。BMIPP的摄取明显低于Tl（p = 0.001）。BMIPP活性降低的程度大于Tl（p < 0.001）。我们得出结论，BMIPP显像在检测不稳定型心绞痛患者的罪犯病变方面表现出色。BMIPP单光子发射计算机断层显像（SPECT）是检测Tl显像无法检测到的短暂性心肌缺血的敏感方法。
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