Driessen O, Höppener R
Eur Neurol. 1977;15(3):135-42. doi: 10.1159/000114802.
In a group of 65 epileptic outpatients the reliability of intake of prescribed medication was evaluated according to two criteria. The following results were obtained: the number of patients with no or irregular intake of antiepileptic drugs in the whole group was 28%; the relationship between dose and observed plasma levels in patients reliable to intake could be verified; physicians were more often aware of unreliable intake by their patients than could be expected by chance.
在一组65名癫痫门诊患者中，根据两项标准评估了规定药物摄入量的可靠性。得到以下结果：在整个组中，未服用或不规律服用抗癫痫药物的患者数量为28%；对于药物摄入量可靠的患者，剂量与观察到的血浆水平之间的关系可以得到验证；医生比偶然预期的情况更经常意识到患者的药物摄入量不可靠。
