Eĭsaev B A
Probl Tuberk. 1995(6):20-2.
Phenotyping of haptoglobin Hp has been performed in 74 patients with recurrent tuberculosis. In patients with recurrences homozygous variant of phenotype Hp 2-2 occurs more frequently, while heterozygous variant Hp 2-1 less frequently. In carriers of phenotype Hp 2-2 recurrent tuberculosis is found more frequently, runs more seriously, heals in the presence of destruction less actively. These reasons underlie high incidence of chronic forms. Subjects with Hp 2-2 (55.3%) need special attention in conduction of recurrence prophylaxis. In carriers of phenotype Hp 2-1 pulmonary tuberculosis relapses less frequently, runs less seriously, resists to treatment rarely.