Turintsev B B, Skorniakov S N, Chugaev Iu P
Probl Tuberk. 1995(6):38-41.
45 patients with pulmonary tuberculosis, 15 patients with acute pneumonia and 15 healthy controls were examined using polarization microscopy of blood serum and blood serum + tuberculin. The serum from healthy subjects contains optically active structures, while that from patients has also pathological structures. Frequency of detection, quantitative and qualitative composition of pathological structures in tuberculosis are related to the disease phase and decline with the activity inhibition. Examination of native serum is not able to distinguish specific from nonspecific processes in the lungs. The addition of tuberculin to native serum helped detect subclinical tuberculosis. Polarization microscopy of native serum is recommended for control of pulmonary tuberculosis and treatment efficacy, modification with tuberculin may be used as an additional test for determination of the disease activity and for differential diagnosis with acute pneumonia.
对45例肺结核患者、15例急性肺炎患者和15名健康对照者采用血清偏振显微镜检查以及血清+结核菌素检查。健康受试者的血清含有光学活性结构，而患者的血清也有病理结构。肺结核中病理结构的检出频率、定量和定性组成与疾病阶段相关，并随着活动抑制而下降。对天然血清的检查无法区分肺部的特异性和非特异性过程。在天然血清中添加结核菌素有助于检测亚临床肺结核。建议采用天然血清偏振显微镜检查来控制肺结核及治疗效果，结核菌素修饰可作为确定疾病活动度及与急性肺炎进行鉴别诊断的附加检查。
