CD28共刺激调节编码高亲和力白细胞介素2受体的三个基因（α、β、γ）的长期表达。 - Suppr

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超能文献

CD28 costimulation regulates long-term expression of the three genes (alpha, beta, gamma) encoding the high-affinity IL2 receptor.

作者信息

Cerdan C, Martin Y, Courcoul M, Mawas C, Birg F, Olive D

机构信息

Unit 119, National Institute of Health and Medical Research (INSERM), Marseille, France.

出版信息

Res Immunol. 1995 Mar-Apr;146(3):164-8. doi: 10.1016/0923-2494(96)80251-3.

DOI:10.1016/0923-2494(96)80251-3

PMID:8525047

Abstract

摘要

相似文献

CD28 costimulation regulates long-term expression of the three genes (alpha, beta, gamma) encoding the high-affinity IL2 receptor.CD28共刺激调节编码高亲和力白细胞介素2受体的三个基因（α、β、γ）的长期表达。

Res Immunol. 1995 Mar-Apr;146(3):164-8. doi: 10.1016/0923-2494(96)80251-3.

Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule.重组免疫受体介导的肿瘤特异性T细胞激活：高效分泌白细胞介素-2同时需要CD3 ζ信号传导和CD28共刺激，并且可将它们整合到一个联合的CD28/CD3 ζ信号受体分子中。

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The role of CD28 in the activation of T lymphocytes to proliferate in response to IL4.CD28在T淋巴细胞响应IL4激活并增殖过程中的作用。

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CD28 costimulation up-regulates long-term IL-2R beta expression in human T cells through combined transcriptional and post-transcriptional regulation.CD28共刺激通过转录和转录后联合调控上调人T细胞中白细胞介素-2受体β（IL-2Rβ）的长期表达。

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Prolonged IL-2 receptor alpha/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and post-transcriptional regulation.经黏附分子CD2和CD28激活T细胞后，白细胞介素-2受体α/CD25表达延长。转录和转录后联合调控的证明。

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Costimulation: building an immunological synapse.共刺激：构建免疫突触。

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Dynamic regulation of CD28 conformation and signaling by charged lipids and ions.带电脂质和离子对 CD28 构象和信号的动态调节。

Nat Struct Mol Biol. 2017 Dec;24(12):1081-1092. doi: 10.1038/nsmb.3489. Epub 2017 Oct 23.

T-cell activation by recombinant receptors: CD28 costimulation is required for interleukin 2 secretion and receptor-mediated T-cell proliferation but does not affect receptor-mediated target cell lysis.重组受体介导的T细胞激活：白细胞介素2分泌和受体介导的T细胞增殖需要CD28共刺激，但不影响受体介导的靶细胞裂解。

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Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes.抗原依赖性CD28信号传导选择性增强基因改造的活化人原代T淋巴细胞的存活和增殖。

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