CD80（B7-1）和CD86（B7-2）：免疫治疗的潜在靶点？ - Suppr

Suppr

超能文献

CD80 (B7-1) and CD86 (B7-2): potential targets for immunotherapy?

作者信息

van Gool S W, Barcy S, Devos S, Vandenberghe P, Ceuppens J L, Thielemans K, de Boer M

机构信息

Department of Pathophysiology, Catholic University of Leuven, Belgium.

出版信息

Res Immunol. 1995 Mar-Apr;146(3):183-96. doi: 10.1016/0923-2494(96)80256-2.

DOI:10.1016/0923-2494(96)80256-2

PMID:8525052

Abstract

摘要

相似文献

CD80 (B7-1) and CD86 (B7-2): potential targets for immunotherapy?CD80（B7-1）和CD86（B7-2）：免疫治疗的潜在靶点？

Res Immunol. 1995 Mar-Apr;146(3):183-96. doi: 10.1016/0923-2494(96)80256-2.

The complexities of T-cell co-stimulation: CD28 and beyond.T细胞共刺激的复杂性：CD28及其他

Immunol Rev. 1996 Oct;153:155-82. doi: 10.1111/j.1600-065x.1996.tb00924.x.

Could expression of co-stimulatory molecules on B-PBL condition the acceptance or rejection of human liver grafts?B淋巴细胞来源的外周血淋巴细胞（B-PBL）上共刺激分子的表达会影响人肝移植的接受或排斥吗？

Transplant Proc. 2001 Feb-Mar;33(1-2):1384-5. doi: 10.1016/s0041-1345(00)02520-3.

Blocking CD40 - CD154 and CD80/CD86 - CD28 interactions during primary allogeneic stimulation results in T cell anergy and high IL-10 production.在初次同种异体刺激过程中阻断CD40 - CD154和CD80/CD86 - CD28相互作用会导致T细胞无能并产生大量白细胞介素-10。

Eur J Immunol. 1999 Aug;29(8):2367-75. doi: 10.1002/(SICI)1521-4141(199908)29:08<2367::AID-IMMU2367>3.0.CO;2-3.

Treatment of autoimmunity by inhibition of T cell costimulation.通过抑制T细胞共刺激来治疗自身免疫

Adv Exp Med Biol. 2001;490:113-7. doi: 10.1007/978-1-4615-1243-1_12.

Regulation of T and B cell responses by modulating interactions between CD28/CTLA4 and their ligands, CD80 and CD86.通过调节CD28/CTLA4与其配体CD80和CD86之间的相互作用来调节T细胞和B细胞反应。

Ann N Y Acad Sci. 1997 Apr 5;815:392-400. doi: 10.1111/j.1749-6632.1997.tb52090.x.

CD28/CTLA-4 receptor structure, binding stoichiometry and aggregation during T-cell activation.T细胞激活过程中的CD28/CTLA-4受体结构、结合化学计量和聚集

Res Immunol. 1995 Mar-Apr;146(3):130-40. doi: 10.1016/0923-2494(96)80246-x.

New protein steals the show as 'costimulator' of T cells.新型蛋白质作为T细胞的“共刺激分子”成为焦点。

Science. 1993 Nov 5;262(5135):844-5. doi: 10.1126/science.7694360.

Expression of costimulatory molecules CD80 and CD86 and their receptors CD28, CTLA-4 on malignant ascites CD3+ tumour-infiltrating lymphocytes (TIL) from patients with ovarian and other types of peritoneal carcinomatosis.共刺激分子CD80和CD86及其受体CD28、CTLA-4在卵巢癌及其他类型腹膜癌患者恶性腹水中CD3⁺肿瘤浸润淋巴细胞（TIL）上的表达。

Clin Exp Immunol. 2000 Jan;119(1):19-27. doi: 10.1046/j.1365-2249.2000.01105.x.

Transplantation and the CD28/CTLA4/B7 pathway.移植与CD28/CTLA4/B7信号通路

Transplant Proc. 2001 Feb-Mar;33(1-2):209-11. doi: 10.1016/s0041-1345(00)01977-1.

引用本文的文献

Integrating machine learning algorithms and multiple immunohistochemistry validation to unveil novel diagnostic markers based on costimulatory molecules for predicting immune microenvironment status in triple-negative breast cancer.整合机器学习算法和多重免疫组化验证，以揭示基于共刺激分子的新型诊断标志物，用于预测三阴性乳腺癌的免疫微环境状态。

Front Immunol. 2024 Jun 28;15:1424259. doi: 10.3389/fimmu.2024.1424259. eCollection 2024.

Integrated analysis reveals the potential of cluster of differentiation 86 as a key biomarker in high-grade glioma.综合分析揭示了分化群 86 作为高级别神经胶质瘤关键生物标志物的潜力。

Aging (Albany NY). 2023 Dec 26;15(24):15402-15418. doi: 10.18632/aging.205359.

The expression pattern of Immune checkpoints after chemo/radiotherapy in the tumor microenvironment.免疫检查点在肿瘤微环境中经放化疗后的表达模式。

Front Immunol. 2022 Jul 28;13:938063. doi: 10.3389/fimmu.2022.938063. eCollection 2022.

Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury.间充质干细胞通过激活 Notch 信号诱导 LPS 诱导的急性肺损伤中的调节性树突状细胞。

J Transl Med. 2020 Jun 16;18(1):241. doi: 10.1186/s12967-020-02410-z.

Lentiviral delivery of CTLA-4 shRNA improves the expansion of cytokine-induced killer cells and enhances cytotoxic activity .慢病毒介导的CTLA-4短发夹RNA可促进细胞因子诱导的杀伤细胞的扩增并增强其细胞毒活性。

Oncol Lett. 2018 Jan;15(1):741-746. doi: 10.3892/ol.2017.7376. Epub 2017 Nov 9.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验