促甲状腺激素释放激素对大鼠实验性胰腺炎的影响。

Influence of thyrotropin-releasing hormone on experimental pancreatitis in rats.

作者信息

Alhan E, Küçüktülü U, Calik A, Cinel A

机构信息

Department of Surgery, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.

出版信息

Res Exp Med (Berl). 1995;195(4):243-8. doi: 10.1007/BF02576794.

DOI:10.1007/BF02576794

PMID:8525075

Abstract

The main purpose of this study was to investigate the influence of thyroid releasing hormone on acute sodium-taurocholate-induced pancreatitis in rats. Thyroid-releasing hormone did not change the survival rate, serum amylase, glucose calcium, liver transaminases levels or the degree of pancreatic damage, but reduced lactate dehydrogenase. Our findings suggest that the use of thyroid-releasing hormone has no beneficial effect on the course of acute experimental pancreatitis.

摘要

本研究的主要目的是探讨促甲状腺激素释放激素对大鼠急性牛磺胆酸钠诱导的胰腺炎的影响。促甲状腺激素释放激素并未改变存活率、血清淀粉酶、血糖、血钙、肝转氨酶水平或胰腺损伤程度，但降低了乳酸脱氢酶水平。我们的研究结果表明，使用促甲状腺激素释放激素对急性实验性胰腺炎的病程没有有益影响。