[脑血管意外与艾滋病]

[Cerebrovascular accidents and AIDS].

作者信息

Strobel M, Lamaury I, Brouzes F, Léonardi C, Dorak B, Sow M T, Pelczar S, Roul S, Cnudde F, Gabriel J M

机构信息

Service des maladies infectieuses et CISIH, CHRU, Guadeloupe, France.

出版信息

Rev Med Interne. 1995;16(10):743-6. doi: 10.1016/0248-8663(96)80782-x.

DOI:10.1016/0248-8663(96)80782-x

PMID:8525153

Abstract

A number of pathological and clinical data suggest that AIDS could be an underestimated cause of cerebro-vascular disease, especially in young individuals. Eight retrospective cases of stroke in AIDS patients are reported. Mean age was 39 years, mean CD4 cells count 57/mm3. Pathogenic mechanism, particularly the role of opportunistic infections remains unclear. Prognosis does not seem constantly pejorative: only one patient died from stroke, six are still alive with a 6 months follow-up, without relapse and with minor or no sequellae. Alcohol or cocaine (crack) abuse was present in half the cases. The role of specific risk factors and consequently adapted prophylaxis is questionned.

摘要

大量病理和临床数据表明，艾滋病可能是脑血管疾病一个被低估的病因，尤其是在年轻人中。本文报告了8例艾滋病患者中风的回顾性病例。平均年龄为39岁，平均CD4细胞计数为57/mm³。发病机制，特别是机会性感染的作用仍不清楚。预后似乎并非总是恶化：只有1例患者死于中风，6例在6个月的随访中仍存活，无复发且有轻微后遗症或无后遗症。半数病例存在酒精或可卡因（快克）滥用情况。特定风险因素的作用以及相应的预防性措施受到质疑。