Thumasupapong S, Tin T, Sukontason K, Sawaddichi C, Karbwang J
Pra Pok Klao Hospital, Chantaburi, Thailand.
Southeast Asian J Trop Med Public Health. 1995 Mar;26(1):34-7.
Electroencephalography (EEG) was performed in 13 male patients with cerebral malaria during the first 24 hours of admission, using a 10-channel, 10-20 system EEG machine (6 montages, 20 minute duration). The EEG patterns were of theta and delta waves from both sides of cerebral hemisphere suggesting diffused cortical dysfunction. No epileptic pattern was found in patients who had seizures prior to, or after admission. The initial EEG performed on the day of admission did not show any specific pattern attributable to any pathological condition. It was also unable to predict the prognosis of the 2 dead patients. However, one cerebral malaria patient with left hemiplegia was subsequently found to have right basal ganglia hemorrhage in CAT scan, high amplitude delta waves and theta waves in the tracings of the right hemisphere. The study suggests that a single EEG data on admission can hardly give enough information for prediction of the clinical course and outcome of cerebral malaria. Serial EEGs probably provide more useful information regarding the prognostic signs in this group of patients. Nevertheless, EEG could be useful to rule out some cerebral pathology such as space occupying lesions, epilepsy or any other causes of unconsciousness that could produce similar cerebral symptoms in malaria patients.
对13例脑型疟男性患者在入院后的头24小时内进行了脑电图(EEG)检查,使用的是一台10通道、10-20系统的脑电图机(6种导联组合,持续时间20分钟)。脑电图模式显示大脑半球两侧出现θ波和δ波,提示弥漫性皮质功能障碍。在入院前或入院后发生癫痫发作的患者中未发现癫痫样模式。入院当天进行的首次脑电图检查未显示任何可归因于任何病理状况的特定模式。它也无法预测2例死亡患者的预后。然而,一名患有左侧偏瘫的脑型疟患者随后在计算机断层扫描(CAT)中被发现右侧基底节出血,右侧半球的脑电图描记图中出现高振幅δ波和θ波。该研究表明,入院时单次脑电图数据几乎无法为预测脑型疟的临床病程和结果提供足够信息。系列脑电图检查可能会为该组患者的预后征象提供更有用的信息。尽管如此,脑电图对于排除一些脑部病变,如占位性病变、癫痫或任何其他可能在疟疾患者中产生类似脑部症状的昏迷原因可能是有用的。