[Effect of phepracet and its derivatives on the development of neurogenic dystrophy of the stomach wall and the concentration of noradrenaline in it].

The "weighted" phenamine derivatives--phepracet (beta-phenyl isopropylamide of paraaminophenylacetic acid) and preparations IZM-611 ((phenylisopropylamide of paradipropylaminophenylacetic acid) and IZM-487 (phenylisopropylamide of paradietylaminophenylacetic acid) positively prevented the development of hemorrhagic erosions in the gastric wall and forced down the nerepinephrine level in it caused by a 3-hour electric stimulation of immobilized rats. The greatest prophylactic effect produced the preparation IZM-611. A direct relation between intensity of the antiulcerous action of the drugs and their ability to block the reticular formations of the midbrain was noted.