Gutmann E J
Department of Pathology, Medical College of Wisconsin, Milwaukee 53226, USA.
Am J Clin Pathol. 1995 Dec;104(6):643-7. doi: 10.1093/ajcp/104.6.643.
Two women, ages 42 and 46, each had a cervical mass that clinically was grossly compatible with invasive carcinoma. Colposcopy supported the clinical impression. Weeks after the women were examined, it was determined that the masses represented syphilitic cervicitis. This entity has received almost no attention in the cytology literature, and is not discussed in major cytopathology texts. Accordingly, the cervicovaginal smears that were obtained in these cases are of interest. The smear pattern, which included lymphocytes, plasma cells, histiocytes, and debris, is described. Although in contrast, the histopathology of syphilitic cervicitis is well-characterized, diagnostic evidence of syphilis was missed in the initial interpretation of several of the biopsies. Syphilis recently has reemerged as a public health problem. Although the cases reported here represent rare events, pathologists should be aware that syphilitic cervicitis may clinically and colposcopically simulate a primary advanced cervical cancer. When interpreting cervical biopsies and cervicovaginal smears, they should be alert to patterns that suggest that syphilis is present.
两名女性，年龄分别为42岁和46岁，每人都有一个宫颈肿物，临床检查结果与浸润性癌大致相符。阴道镜检查结果支持临床诊断。在对这两名女性进行检查几周后，确定肿物为梅毒性宫颈炎。该病变在细胞学文献中几乎未受到关注，主要的细胞病理学教材中也未对其进行讨论。因此，这两例病例中获取的宫颈阴道涂片很值得关注。本文描述了涂片的细胞形态，包括淋巴细胞、浆细胞、组织细胞和细胞碎片。尽管与之相反，梅毒性宫颈炎的组织病理学特征明显，但在最初对几份活检标本的解读中却漏诊了梅毒的诊断依据。梅毒最近再次成为一个公共卫生问题。尽管此处报告的病例属于罕见情况，但病理学家应意识到，梅毒性宫颈炎在临床和阴道镜检查中可能会模拟原发性晚期宫颈癌。在解读宫颈活检和宫颈阴道涂片时，他们应警惕提示梅毒存在的细胞形态。
