André B, Scherens B
Laboratoire de Physiologie Cellulaire et de Génétique des Levures Université Libre de Bruxelles, Belgium.
Biochem Biophys Res Commun. 1995 Dec 5;217(1):150-3. doi: 10.1006/bbrc.1995.2757.
The YBR235w gene of the yeast Saccharomyces cerevisiae was found during sequencing of chromosome II. Here, we show that the 1120 aa protein (Ybr235p) encoded by this gene shares strong sequence similarity with the highly related electroneutral Na(+)-C1- and Na(+)-K(+)-C1- cotransporters of animal cells. We hypothesize that this yeast protein also mediates active uptake of C1- into the cell.
酿酒酵母的YBR235w基因是在对二号染色体进行测序时发现的。在此，我们表明该基因编码的1120个氨基酸的蛋白质（Ybr235p）与动物细胞中高度相关的电中性Na(+)-Cl-和Na(+)-K(+)-Cl-共转运体具有很强的序列相似性。我们推测这种酵母蛋白也介导Cl-主动摄取进入细胞。
