Habib O M, Moawad E B, Girges M M, el-Shafei A M
Chemistry Department, Mansoura Faculty of Science, Egypt.
Boll Chim Farm. 1995 Oct;134(9):503-8.
Fourteen of nitrogeneous heterocyclic compounds that accommodate the sulfonate-ester moiety were synthesized through interaction of 2-benzenesulfonylo xyphenyl-3,1-benzoxazine-4-one with some nucleophilic reagents. The assigned structures for the prepared new compounds were confirmed on the basis of elemental and spectral data. Evaluation of the antimicrobial activity of these products, relative to standard antibiotics was tested and discussed.
通过2-苯磺酰氧基苯基-3,1-苯并恶嗪-4-酮与一些亲核试剂的相互作用,合成了十四种含有磺酸酯部分的含氮杂环化合物。根据元素和光谱数据确定了所制备新化合物的指定结构。测试并讨论了这些产品相对于标准抗生素的抗菌活性。