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小鼠输卵管下段平滑肌细胞在孕期和产后的形态学变化。

Morphological changes in the smooth muscle cells of the mouse lower oviduct during pregnancy and post-partum.

作者信息

Faussone-Pellegrini M S, Matini P, Bani G

机构信息

Department of Human Anatomy, University of Florence, Italy.

出版信息

Arch Histol Cytol. 1995 Aug;58(3):293-301. doi: 10.1679/aohc.58.293.

DOI:10.1679/aohc.58.293
PMID:8527236
Abstract

The muscle coat of the lower region of the mouse oviduct undergoes morphological changes during pregnancy and post-partum. Ultrastructural examination and morphometrical findings show that, during pregnancy, the smooth muscle cells undergo a significant increase in both the number of mitochondria and caveolae and in the extension of the rough endoplasmic reticulum and Golgi apparatus, suggesting an enhancement of metabolic activities, especially protein synthesis. Within two days after delivery, the number of mitochondria and caveolae is similar to that of non-pregnant mice, whereas the extension of the rough endoplasmic reticulum and Golgi apparatus further increases significantly. The cytological signs of enhanced protein synthesis in the smooth muscle cells of the lower oviduct during pregnancy and, especially, in the post-partum period are probably related to a remodelling of the intercellular connective tissue matrix.

摘要

小鼠输卵管下段的肌层在妊娠和产后会发生形态学变化。超微结构检查和形态计量学结果表明,在妊娠期间,平滑肌细胞的线粒体和小窝数量显著增加,粗面内质网和高尔基体的延伸也增加,这表明代谢活动增强,尤其是蛋白质合成。分娩后两天内,线粒体和小窝的数量与未怀孕小鼠相似,而粗面内质网和高尔基体的延伸进一步显著增加。妊娠期间,尤其是产后,输卵管下段平滑肌细胞中蛋白质合成增强的细胞学迹象可能与细胞间结缔组织基质的重塑有关。

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Arch Histol Cytol. 1995 Aug;58(3):293-301. doi: 10.1679/aohc.58.293.
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